The GATE Grind

GATE 2026 BT – Question 28

General Biology · Biochemistry: Biomolecules, biological membranes, channels and pumps, molecular motors, action potential and transport · 1 mark · Multiple select

Which of the following drugs inhibit(s) ATP-ADP translocase?

  1. Oligomycin
  2. Atractyloside
  3. Amytal
  4. Bongkrekic acid

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Correct answer: (B) Atractyloside; (D) Bongkrekic acid

Explanation

Atractyloside and bongkrekic acid block the ATP-ADP translocase of the inner mitochondrial membrane. Oligomycin blocks the $F_0$ part of ATP synthase, and amytal inhibits complex I.