The GATE Grind

GATE 2024 BT – Question 18

General Biology · Immunology: Lymphoid organs, innate immunity, inflammation, cytokines, chemokines and the complement system · 1 mark · Multiple choice

2-mercaptoethanol breaks the ________ covalent bond between light and heavy chains of an immunoglobulin molecule.

  1. C-N
  2. N-O
  3. S-C
  4. S-S

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Correct answer: (D) S-S

Explanation

The chains are held together by disulphide (S-S) bonds, which the reducing agent 2-mercaptoethanol cleaves.