GATE 2022 BT – Question 54
Which of the following statement(s) regarding trafficking in eukaryotic cells is(are) CORRECT?
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Correct answer: (A) Dynamin binds GTP and is involved in vesicle budding; (B) Dynamin is involved in cytoskeletal remodelling; (C) Dynein binds ATP and is involved in movement of organelles along microtubules
Explanation
Check each statement about membrane trafficking proteins.
- **A. Dynamin binds GTP and is involved in vesicle budding.** True. Dynamin is a GTPase that forms a collar around the neck of a budding vesicle and pinches it off. ✓
- **B. Dynamin is involved in cytoskeletal remodelling.** True. Dynamin also interacts with actin and helps to remodel it. ✓
- **C. Dynein binds ATP and moves organelles along microtubules.** True. Dynein is a motor protein that uses ATP hydrolysis to move towards the minus end of microtubules. ✓
- **D. Dynein binds GTP...** False. Dynein is powered by ATP, not GTP.
Answer **A, B and C**.