The GATE Grind

GATE 2025 BM – Question 46

Mammalian Cell Biology, Human Anatomy and Physiology · Nervous System · 2 marks · Multiple select

Which statements about neuronal membranes and action potentials are correct?

  1. Outward current depolarizes the membrane
  2. Inward current depolarizes the membrane
  3. Stronger stimulus increases action-potential amplitude
  4. Stronger stimulus decreases action-potential latency

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Correct answer: (B) Inward current depolarizes the membrane; (D) Stronger stimulus decreases action-potential latency

Explanation

Under the conventional positive-charge current definition, inward current makes the interior less negative, depolarizing it. Once threshold is reached, the spike is approximately all-or-none rather than increasing its amplitude with stimulus strength. Stronger stimulation generally reaches threshold earlier, shortening latency. Thus B,D.

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