A microorganism isolated from a salt-rich lake (salt concentration approximately 2 M) has diglycerol tetraethers with polyisoprenoid alcohol side chains as the major membrane lipid. It is
Ether-linked isoprenoid membrane lipids are characteristic of archaea. Tetraether lipids can span the membrane and support stability in challenging environments, consistent with the salt-rich habitat. The bacterial and eukaryotic alternatives typically use different membrane lipid chemistry. The distinctive lipid structure therefore identifies D.
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