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GATE 2026 BT – Question 48

Genetics, Cellular and Molecular Biology · Molecular Biology: Structure of genes and chromosomes, mutations and mutagenesis, regulation of gene expression · 2 marks · Multiple select

Which of the following is/are posttranslational modification(s) involved in epigenetic control of gene expression?

  1. Arginine methylation
  2. Lysine acetylation
  3. Cytosine methylation
  4. Cytosine deamination

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Show answer and explanation

Correct answer: (A) Arginine methylation; (B) Lysine acetylation

Explanation

Methylation of arginine and acetylation of lysine are modifications of histone proteins after translation that control gene expression. Cytosine methylation is a modification of DNA, not of a protein, and cytosine deamination is a form of DNA damage.