A 65 kg adult with 65-year lifetime drinks2 L/day for five years from water containing.15 mg/L toluene. Reference dose.200 mg/(kg·day). Find noncancer hazard quotient, to three decimals.
Average daily dose during the exposure period is $ADD=CI/BW=.15(2)/65=.00461538$ mg/(kg·day). Noncancer hazard quotient is $HQ=ADD/RfD=.00461538/.200=.0230769$,rounded **.023**. Exposure duration cancels when averaging over the same five-year noncancer exposure interval; lifetime averaging would answer a different risk question.
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