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GATE 2024 BM – Question 20

Biomaterials and Tissue Engineering · Biocompatibility and Implant Characteristics · 1 mark · Multiple choice

Which cumulative drug-release curve is ideal for an implantable slow-release delivery device?

Diagram for GATE 2024 BM question 20
  1. Option A in the figure
  2. Option B in the figure
  3. Option C in the figure
  4. Option D in the figure

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Show answer and explanation

Correct answer: (B) Option B in the figure

Explanation

A constant release rate produces cumulative released drug increasing linearly with time, the zero-order profile. B is the straight rising curve. Curves with an early burst and plateau have declining release rate, while decreasing cumulative release is not a valid ordinary cumulative profile. Thus B.

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