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GATE 2019 BT – Question 63

Fundamentals of Biological Engineering · Downstream Processing: Filtration, centrifugation, cell disruption, chromatography, extraction, adsorption and drying · 2 marks · Numerical answer

In cross-flow filtration, pressure drop driving feed flow is 2 atm, inlet pressure 3 atm and filtrate pressure atmospheric (1 atm). Find average transmembrane pressure drop in atm.

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Correct answer: 1 to 1

Explanation

Outlet feed-side pressure is $P_o=P_i-\Delta P=3-2=1$ atm. The mean feed-side pressure is (3+1)/2 = 2 atm. Subtract filtrate pressure to obtain $\Delta P_m=(P_i+P_o)/2-P_f=2-1=1$ atm. Axial pressure drop and transmembrane pressure are different quantities.

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