The GATE Grind

GATE 2025 BT – Question 40

Genetics, Cellular and Molecular Biology · Molecular Biology: Replication, transcription, splicing, translation, non-coding and micro RNA, RNA interference, DNA damage and repair · 2 marks · Multiple choice

Correctly match the Enzyme with its respective Function.

EnzymeFunction
P. Gyrase1. Removes a damaged base by cleaving the bond between sugar and base
Q. Deadenylase2. Provides a swivel allowing one DNA strand to rotate around the other
R. Glycosylase3. Catalyses bond formation between 3'-OH and 5'-phosphate end of nucleotides in duplex DNA
S. DNA ligase4. Is an exoribonuclease that removes the poly(A) tail
  1. P-2; Q-4; R-1; S-3
  2. P-1; Q-4; R-2; S-3
  3. P-2; Q-1; R-4; S-3
  4. P-3; Q-2; R-1; S-4

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Correct answer: (A) P-2; Q-4; R-1; S-3

Explanation

Gyrase is a topoisomerase that allows the strands to swivel (2). Deadenylase trims the poly(A) tail (4). A DNA glycosylase cuts the sugar-base bond of a damaged base (1). DNA ligase joins a 3'-OH to a 5'-phosphate (3).