GATE Genetics, Cellular and Molecular Biology: Molecular Biology: Replication, transcription, splicing, translation, non-coding and micro RNA, RNA interference, DNA damage and repair – Previous Year Questions

17 GATE previous year questions on Molecular Biology: Replication, transcription, splicing, translation, non-coding and micro RNA, RNA interference, DNA damage and repair (Genetics, Cellular and Molecular Biology, Biotechnology) with answers and explanations, from every paper.

1. GATE 2021 BT Q12 (1 mark, Multiple choice) – The enzyme transcribing eukaryotic genes encoding the precursor of 28S, 18S and 5.8S rRNAs is
2. GATE 2021 BT Q27 (1 mark, Multiple choice) – The process using RNA-induced silencing complex to block gene expression is
3. GATE 2022 BT Q21 (1 mark, Multiple choice) – In animal cells, the endogenously produced miRNAs silence gene expression by
4. GATE 2022 BT Q46 (2 marks, Multiple choice) – Adenine can undergo a spontaneous change to hypoxanthine in a cell, leading to a DNA base pair mismatch. The CORRECT combination of enzymes that are…
5. GATE 2023 BT Q11 (1 mark, Multiple choice) – Eukaryotic transcription is carried out by
6. GATE 2023 BT Q13 (1 mark, Multiple choice) – Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]. Assertion [a]: In multicellular organisms, cells of…
7. GATE 2023 BT Q25 (1 mark, Multiple choice) – Match the types of RNA in Group I with their corresponding function in Group II. Group I Group II --- --- P. mRNA 1. Serves as adaptors between mRNA…
8. GATE 2026 BT Q22 (1 mark, Multiple choice) – The RNA primer synthesized during bacterial DNA replication is removed by .
9. GATE 2026 BT Q42 (2 marks, Multiple select) – Messenger RNAs (mRNAs) translate to generate polypeptides and the translation terminates at the UGA, UAG or UAA stop codons. The AGA codon acts as…
10. GATE 2025 BT Q16 (1 mark, Multiple choice) – Which one of the following is true for piRNAs?
11. GATE 2025 BT Q22 (1 mark, Multiple select) – Which of the following enzymes is/are involved in the biogenesis of miRNA?
12. GATE 2025 BT Q40 (2 marks, Multiple choice) – Correctly match the Enzyme with its respective Function. Enzyme Function --- --- P. Gyrase 1. Removes a damaged base by cleaving the bond between…
13. GATE 2025 BT Q50 (2 marks, Multiple select) – Which of the following statements about initiation of DNA replication in eukaryotes is/are true?
14. GATE 2025 BT Q52 (2 marks, Multiple select) – Which of the following statements is/are true about telomerase?
15. GATE 2024 BT Q38 (2 marks, Multiple choice) – Match the enzyme (Column I) with its corresponding function (Column II). Column I Column II --- --- P. Primase 1. RNA dependent RNA synthesis Q.…
16. GATE 2024 BT Q50 (2 marks, Multiple select) – Which of the following statements regarding the below mentioned mRNA sequence is/are TRUE? 5'-UGAUGAGCCUUAACCGGGAACGAAUUUAAG-3'
17. GATE 2024 BT Q51 (2 marks, Multiple select) – Which of the following conditions induce(s) the expression of β-galactosidase gene in the lac operon?