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GATE 2022 BT – Question 50

Fundamentals of Biological Engineering · Bioreaction Engineering: Rate law, zero and first order kinetics, Michaelis-Menten kinetics and enzyme inhibition · 2 marks · Multiple select

Which plots are correct for Michaelis–Menten kinetics at $[S]\ll K_m$, where S is substrate concentration and $v_0$ is initial reaction velocity?

source diagram and its labels are reproduced in the attached image.
  1. Option A in the figure
  2. Option B in the figure
  3. Option C in the figure
  4. Option D in the figure

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Show answer and explanation

Correct answer: (A) Option A in the figure; (D) Option D in the figure

Explanation

For $[S]\ll K_m$, $v_0=(V_{max}/K_m)[S]$ is linear and first-order substrate depletion is exponential. Thus A and D match.