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GATE 2026 BM – Question 36

Biomaterials and Tissue Engineering · Biocompatibility and Implant Characteristics · 2 marks · Multiple choice

A drug is loaded into a polymeric device. Which ratio defines encapsulation efficiency?

  1. Successfully loaded drug / Polymer in device
  2. Successfully loaded drug / Drug used in process
  3. Drug used in process / Successfully loaded drug
  4. Polymer in device / Drug used in process

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Correct answer: (B) Successfully loaded drug / Drug used in process

Explanation

Encapsulation efficiency measures the fraction of the initially supplied drug retained successfully in the carrier. Its denominator is the drug used, not polymer mass. Therefore B; multiplying by one hundred expresses this fraction as a percentage. Drug-to-carrier ratios measure loading rather than capture efficiency.

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