GATE 2020 BT – Question 39

Genetics, Cellular and Molecular Biology · Cell Biology: Eukaryotic cell structure, cell cycle and growth control, cell-cell communication, signalling and signal transduction · 2 marks · Multiple choice

Which statements about the eukaryotic cell cycle are CORRECT?

[P] CDKs can phosphorylate proteins in the absence of cyclins.

[Q] CDKs can be inactivated by phosphorylation.

[R] Cyclin degradation is required for cell-cycle progression.

[S] CDKs are not involved in chromosome condensation.

P and R only
P and S only
P, Q and R only
Q and R only

Practise this question in The GATE Grind →

Show answer and explanation

Correct answer: (D) Q and R only

Explanation

Cyclin-dependent kinases require their cyclin partners for normal cell-cycle activity, so P is false. Inhibitory phosphorylation can turn CDKs off, making Q true. Timed cyclin degradation helps make transitions irreversible, so R is true. Mitotic CDKs regulate chromosome-condensation machinery, making S false. The correct combination is Q and R, D.

More Cell Biology: Eukaryotic cell structure, cell cycle and growth control, cell-cell communication, signalling and signal transduction questions

GATE 2020 BT Q48 – Match organelles P mitochondrion, Q chloroplast, R nucleus, S endoplasmic reticulum with…
GATE 2020 BT Q58 – A culture starts with five human fibroblast cells. Two never divide; the other three each…
GATE 2019 BT Q16 – During which phase of the eukaryotic mitotic cell cycle does DNA synthesis occur?
GATE 2019 BT Q38 – Match organelles P lysosome, Q smooth ER, R Golgi apparatus, S nucleolus with functions 1…
GATE 2024 BT Q19 – During normal embryonic development of the mice paw, elimination of cells from the…
GATE 2024 BT Q48 – Under which of the following conditions, a mammalian somatic cell fails to undergo mitosis…

All Cell Biology: Eukaryotic cell structure, cell cycle and growth control, cell-cell communication, signalling and signal transduction questions →