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GATE 2019 BT – Question 53

Fundamentals of Biological Engineering · Bioreaction Engineering: Batch, fed-batch and continuous processes, microbial and enzyme reactors, optimization and scale up · 2 marks · Multiple choice

Which are ALWAYS CORRECT about an ideal chemostat? P internal substrate concentration equals exit concentration; Q optimal dilution is below critical dilution; R biomass concentration rises with dilution; S cell recirculation permits operation beyond critical dilution.

  1. P and Q only
  2. P, R and S only
  3. P and S only
  4. P, Q and S only

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Correct answer: (D) P, Q and S only

Explanation

Perfect mixing gives P. For the usual steady biomass-productivity objective, the optimum occurs below the washout boundary, supporting Q under the intended convention. Recycling retains cells and can allow hydraulic dilution beyond the corresponding no-recycle critical rate, supporting S. R is false in the ordinary Monod chemostat because residual substrate rises and biomass generally falls as washout approaches. The intended combination is P,Q,S, D; the “optimal” statement presumes the conventional productivity objective.

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