The GATE Grind

GATE Recombinant DNA Technology and Other Tools in Biotechnology: Computational tools: Bioinformatics resources, databases, sequence analysis, alignment and phylogeny – Previous Year Questions

10 GATE previous year questions on Computational tools: Bioinformatics resources, databases, sequence analysis, alignment and phylogeny (Recombinant DNA Technology and Other Tools in Biotechnology, Biotechnology) with answers and explanations, from every paper.

  1. GATE 2021 BT Q13 (1 mark, Multiple choice) – Number of unrooted trees in a phylogeny of five sequences is
  2. GATE 2021 BT Q14 (1 mark, Multiple choice) – Which method tests the significance of a predicted phylogeny?
  3. GATE 2021 BT Q42 (2 marks, Multiple choice) – Which tool compares all six reading frames of a nucleotide query with all six reading frames of a nucleotide database?
  4. GATE 2022 BT Q24 (1 mark, Multiple choice) – Which of the following is NOT used for generating an optimal alignment of two nucleotide sequences?
  5. GATE 2022 BT Q44 (2 marks, Multiple choice) – The maximum parsimony method is used to construct a phylogenetic tree for a set of sequences. Which one of the following statements about the method…
  6. GATE 2023 BT Q26 (1 mark, Multiple choice) – Which one of the following programs is used for finding distantly related (or remote) protein homologs?
  7. GATE 2023 BT Q27 (1 mark, Multiple choice) – Which one of the following is used for global alignment of two protein sequences?
  8. GATE 2023 BT Q51 (2 marks, Numerical answer) – If there are three unrooted trees for four protein sequences, the number of rooted trees for the same number of sequences is .
  9. GATE 2026 BT Q30 (1 mark, Multiple select) – BLAST and its extensions can be used to determine similarity of a query protein sequence with which of the following database(s)?
  10. GATE 2025 BT Q47 (2 marks, Multiple choice) – Correctly match the following Bioinformatic tool/Database with its respective Utility. Bioinformatic tool/Database Utility --- --- P. BLAST 1.…